ADAM19 Antikörper (N-Term)

Produktnummer ABIN2783899

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ADAM19 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Pferd und Zebrafisch (Danio rerio).Es wurde in 1 Publikation zitiert.

Kurzübersicht für ADAM19 Antikörper (N-Term) (ABIN2783899)

Target: ADAM19 (Adam19) (ADAM Metallopeptidase Domain 19 (Adam19))

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAM19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ADAM19 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: ADAM19 Antibody - N-terminal region

Sequenz: VADYLEFQKN RRDQDATKHK LIEIANYVDK FYRSLNIRIA LVGLEVWTHG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ADAM19. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ADAM19

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49780-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ADAM19 Antikörper (ABIN2783899)

Marballi, Cruz, Thompson, Walss-Bass: "Differential neuregulin 1 cleavage in the prefrontal cortex and hippocampus in schizophrenia and bipolar disorder: preliminary findings." in: PLoS ONE, Vol. 7, Issue 5, pp. e36431, (2012) (PubMed).

Details zu ADAM19

Target: ADAM19 (Adam19) (ADAM Metallopeptidase Domain 19 (Adam19))

Andere Bezeichnung: ADAM19

Hintergrund:

Background Information: ADAM19 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. Alternative splicing results in two transcript variants.This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. Alternative splicing results in two transcript variants.

Gene Name: ADAM metallopeptidase domain 19

Alternative Symbols: MLTNB, FKSG34, MADDAM

Protein Name: Disintegrin and metalloproteinase domain-containing protein 19

Molekulargewicht: 82kDa

Gen-ID: 8728

NCBI Accession: NP_075525

UniProt: Q9H013