LMBR1 Antikörper (N-Term)

Produktnummer ABIN2783870

Der Kaninchen Polyklonal anti-LMBR1 Antikörper wird verwendet zum Nachweis von LMBR1 in Proben von Human, Maus, Ratte, Rind (Kuh), Kaninchen und Hund. Er wurde validiert für WB.

Kurzübersicht für LMBR1 Antikörper (N-Term) (ABIN2783870)

Target: LMBR1 (Limb Region 1 Homolog (LMBR1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LMBR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LMBR1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: LMBR1 Antibody - N-terminal region

Sequenz: MEGQDEVSAR EQHFHSQVRE STICFLLFAI LYVVSYFIIT RYKRKSDEQE

Homologie: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against LMBR1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LMBR1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104462

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu LMBR1

Target: LMBR1 (Limb Region 1 Homolog (LMBR1))

Andere Bezeichnung: LMBR1

Hintergrund:

Background Information: LMBR1 is a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of LMBR1 gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if LMBR1 gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression.This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Limb region 1 homolog (mouse)

Alternative Symbols: LSS, TPT, ZRS, ACHP, PPD2, THYP, DIF14, C7orf2

Protein Name: Limb region 1 protein homolog

Molekulargewicht: 55kDa

Gen-ID: 64327

NCBI Accession: NP_071903

UniProt: Q8WVP7