RHBDF1 Antikörper (N-Term)

Produktnummer ABIN406075

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RHBDF1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für RHBDF1 Antikörper (N-Term) (ABIN406075)

Target: RHBDF1 (Rhomboid 5 Homolog 1 (RHBDF1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RHBDF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RHBDF1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: RHBDF1 Antibody - N-terminal region

Sequenz: KDWEKAPEQA DLTGGALDRS ELERSHLMLP LERGWRKQKE GAAAPQPKVR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against RHBDF1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RHBDF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49721-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu RHBDF1

Target: RHBDF1 (Rhomboid 5 Homolog 1 (RHBDF1))

Andere Bezeichnung: RHBDF1

Hintergrund:

Background Information: RHBDF1 is a seven-transmembrane protein with a long N-terminal cytoplasmic extension that comprises half of the polypeptide sequence, and is found in the endoplasmic reticulum and Golgi, but not on the cell surface. RHBDF1 has a pivotal role in sustaining growth signals in epithelial cancer cells and thus may serve as a therapeutic target for treating epithelial cancers.

Gene Name: Rhomboid 5 homolog 1 (Drosophila)

Alternative Symbols: Dist1, hDist1, C16orf8, EGFR-RS, gene-89, gene-90

Protein Name: Inactive rhomboid protein 1

Molekulargewicht: 97 kDa

Gen-ID: 64285

NCBI Accession: NP_071895

UniProt: Q96CC6

Pathways: EGFR Signaling Pathway, Growth Factor Binding