SRPRB Antikörper (Middle Region)

Produktnummer ABIN2783830

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SRPRB in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh), Saccharomyces cerevisiae und Zebrafisch (Danio rerio) und wurde in 1 Publikation erwähnt.

Kurzübersicht für SRPRB Antikörper (Middle Region) (ABIN2783830)

Target: SRPRB (Signal Recognition Particle Receptor, B Subunit (SRPRB))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh), Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRPRB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SRPRB Antikörper

Bindungsspezifität: Middle Region

Sequenz: QDIAMAKSAK LIQQQLEKEL NTLRVTRSAA PSTLYSSSTA PAQLGKKGKE

Homologie: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SRPRB. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SRPRB

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 271 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SRPRB Antikörper (ABIN2783830)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Details zu SRPRB

Target: SRPRB (Signal Recognition Particle Receptor, B Subunit (SRPRB))

Andere Bezeichnung: SRPRB

Hintergrund: SRPRB has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.
Alias Symbols: APMCF1
Protein Interaction Partner: ERLIN2, UBC, STAU1, MDM2, FBXO6, PPP6R1, ADRB2, LMNA, UBL4A, CA9, UBE2L3, TAGLN, SPR, SNRPC, S100A10, RRBP1, RPL38, RFX5, RBMS1, PIN4, PFN1, ACAA1, TMED4, TMEM65, RPS10P5, MRRF, SARNP, NABP2, MRPL14, TMBIM1, SUGP1, SBDS, MRPS28, TARDBP, TOMM40, UBE4B, SF3
Protein Size: 271

Molekulargewicht: 30 kDa

Gen-ID: 58477

NCBI Accession: NM_021203, NP_067026

UniProt: Q9Y5M8

Pathways: ER-Nucleus Signaling