NDFIP2 Antikörper (Middle Region)

Produktnummer ABIN2783749

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NDFIP2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Rind (Kuh), Hund, Pferd, Ratte, Zebrafisch (Danio rerio), Meerschweinchen, Schwein und Kaninchen.

Kurzübersicht für NDFIP2 Antikörper (Middle Region) (ABIN2783749)

Target: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Reaktivität: Human, Maus, Rind (Kuh), Hund, Pferd, Ratte, Zebrafisch (Danio rerio), Meerschweinchen, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDFIP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NDFIP2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: SFCITNTIAG RYGAICGFGL SLIKWILIVR FSDYFTGYFN GQYWLWWIFL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against NDFIP2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NDFIP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 336 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NDFIP2

Target: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Andere Bezeichnung: NDFIP2

Hintergrund: NDFIP2 activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, NDFIP2 may control many cellular processes. NDFIP2 recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. NDFIP2 may modulate EGFR signaling.
Alias Symbols: FLJ25842, KIAA1165, N4wbp5a, N4WBP5A
Protein Interaction Partner: UBC, NEDD4L, NEDD4, ELAVL1, ITCH, WWP2, SRC, PTEN, LYN, FYN, EGFR, SMURF1, SLC11A2,
Protein Size: 336

Molekulargewicht: 36 kDa

Gen-ID: 54602

NCBI Accession: NM_019080, NP_061953

UniProt: Q9NV92

Pathways: Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interaktom