UGT1A5 Antikörper (N-Term)
Kurzübersicht für UGT1A5 Antikörper (N-Term) (ABIN2783747)
Target
Alle UGT1A5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- UGT1A5 Antibody - N-terminal region
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Sequenz
- EENFFTLTTY AISWTQDEFD RLLLGHTQSF FETEHLLMKF SRRMAIMNNM
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Homologie
- Human: 100%, Rat: 83%
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Produktmerkmale
- This is a rabbit polyclonal antibody against UGT1A5. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human UGT1A5
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49439-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- UGT1A5 (UDP Glucuronosyltransferase 1 Family, Polypeptide A5 (UGT1A5))
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Andere Bezeichnung
- UGT1A5
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Hintergrund
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Background Information: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter.
Gene Name: UDP glucuronosyltransferase 1 family, polypeptide A5
Alternative Symbols: UDPGT, UGT1E, UDPGT 1-5
Protein Name: UDP-glucuronosyltransferase 1-5
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Molekulargewicht
- 57kDa
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Gen-ID
- 54579
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NCBI Accession
- NP_061951
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UniProt
- P35504
Target
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