PCDHB15 Antikörper (N-Term)

Produktnummer ABIN2783730

Dieses Anti-PCDHB15-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PCDHB15 in WB. Geeignet für Human, Rind (Kuh), Pferd, Schwein und Hund.

Kurzübersicht für PCDHB15 Antikörper (N-Term) (ABIN2783730)

Target: PCDHB15 (Protocadherin beta 15 (PCDHB15))

Reaktivität: Human, Rind (Kuh), Pferd, Schwein, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHB15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PCDHB15 Antikörper

Bindungsspezifität: N-Term

Sequenz: VMEETERGSF VANLANDLGL GVGELAERGA RVVSEDNEQG LQLDLQTGQL

Homologie: Cow: 86%, Dog: 93%, Horse: 86%, Human: 100%, Pig: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PCDHB15. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHB15

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 787 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PCDHB15

Target: PCDHB15 (Protocadherin beta 15 (PCDHB15))

Andere Bezeichnung: PCDHB15

Hintergrund: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
Alias Symbols: PCDH-BETA15
Protein Interaction Partner: UBC,
Protein Size: 787

Molekulargewicht: 83 kDa

Gen-ID: 56121

NCBI Accession: NM_018935, NP_061758

UniProt: Q9Y5E8