CDYL Antikörper (N-Term)

Produktnummer ABIN2783639

Dieser Anti-CDYL Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von CDYL in WB und IF. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Pferd und Meerschweinchen. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für CDYL Antikörper (N-Term) (ABIN2783639)

Target: CDYL (Chromodomain Protein, Y-Like (CDYL))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDYL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-CDYL Antikörper

Bindungsspezifität: N-Term

Sequenz: YIHDFNRRHT EKQKESTLTR TNRTSPNNAR KQISRSTNSN FSKTSPKALV

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against CDYL. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of human CDYL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 544 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CDYL Antikörper (ABIN2783639)

Li, Xia, Huang, Chen, Su, Li, Wang, Ding, Shao: "A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells." in: FEBS letters, Vol. 584, Issue 14, pp. 3198-202, (2010) (PubMed).

Details zu CDYL

Target: CDYL (Chromodomain Protein, Y-Like (CDYL))

Andere Bezeichnung: CDYL

Hintergrund: CDYL acts as repressor of transcription. CDYL has histone acetyltransferase activity, with a preference for histone H4.Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene.
Alias Symbols: CDYL1, DKFZP586C1622, MGC131936
Protein Interaction Partner: UBC, HECW2, HDAC2, HDAC1, MIER1, MIER2, EHMT2, RBBP4, MYC, SUZ12, EZH2, CTBP1, WIZ, ZNF644, SETDB1, SMARCB1, SMARCA4, REST, HIST1H3A, HTRA1,
Protein Size: 544

Molekulargewicht: 60 kDa

Gen-ID: 9425

NCBI Accession: NM_004824, NP_004815

UniProt: Q9Y232