LTC4S Antikörper (N-Term)

Produktnummer ABIN2783616

Der Kaninchen Polyklonal Anti-LTC4S-Antikörper wurde für WB validiert. Er ist geeignet, LTC4S in Proben von Human, Rind (Kuh), Hund, Meerschweinchen, Pferd, Maus, Ratte, Kaninchen und Zebrafisch (Danio rerio) zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für LTC4S Antikörper (N-Term) (ABIN2783616)

Target: LTC4S (Leukotriene C4 Synthase (LTC4S))

Reaktivität: Human, Rind (Kuh), Hund, Meerschweinchen, Pferd, Maus, Ratte, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LTC4S Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LTC4S Antikörper

Bindungsspezifität: N-Term

Sequenz: MKDEVALLAA VTLLGVLLQA YFSLQVISAR RAFRVSPPLT TGPPEFERVY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 92%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against LTC4S. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LTC4S

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 150 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-LTC4S Antikörper (ABIN2783616)

Tang, Sally, Lesko, Discepolo, Abadie, Ciszewski, Semrad, Guandalini, Kupfer, Jabri: "Cysteinyl leukotrienes mediate lymphokine killer activity induced by NKG2D and IL-15 in cytotoxic T cells during celiac disease." in: The Journal of experimental medicine, Vol. 212, Issue 10, pp. 1487-95, (2015) (PubMed).

Details zu LTC4S

Target: LTC4S (Leukotriene C4 Synthase (LTC4S))

Andere Bezeichnung: LTC4S (leukotriene C4 synthase) (LTC4S)

Hintergrund: The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. LTC4S is an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma.The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC33147
Protein Interaction Partner: MGST1, LTC4S, ALOX5AP, ALOX5,
Protein Size: 150

Molekulargewicht: 16 kDa

Gen-ID: 4056

NCBI Accession: NM_145867, NP_665874

UniProt: Q16873

Pathways: Cellular Response to Molecule of Bacterial Origin