TTC5 Antikörper (C-Term)

Produktnummer ABIN2783601

Dieser Anti-TTC5 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von TTC5 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Kaninchen, Meerschweinchen und Pferd.

Kurzübersicht für TTC5 Antikörper (C-Term) (ABIN2783601)

Target: TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Kaninchen, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TTC5 Antikörper

Bindungsspezifität: C-Term

Sequenz: GDSVAIPEPN LRLHRIQHKG KDYSFSSVRV ETPLLLVVNG KPQGSSSQAV

Homologie: Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against TTC5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TTC5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 440 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TTC5

Target: TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))

Andere Bezeichnung: TTC5

Hintergrund: TTC5 is an adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. It is required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. It prevents p53/TP53 degradation by MDM2.
Alias Symbols: Strap
Protein Interaction Partner: AR, NR3C1, ESR1, CAMK2D, CAMK2B, UBC, CAND1, COPS5, CUL3, ELAVL1,
Protein Size: 440

Molekulargewicht: 49 kDa

Gen-ID: 91875

NCBI Accession: NM_138376, NP_612385

UniProt: Q8N0Z6

Pathways: Chromatin Binding