TTC5 Antikörper (C-Term)

Produktnummer ABIN2783601

Dieses Anti-TTC5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TTC5 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Kaninchen, Meerschweinchen und Pferd.

Kurzübersicht für TTC5 Antikörper (C-Term) (ABIN2783601)

Target: TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Kaninchen, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TTC5 Antikörper

Bindungsspezifität: C-Term

Sequenz: GDSVAIPEPN LRLHRIQHKG KDYSFSSVRV ETPLLLVVNG KPQGSSSQAV

Homologie: Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against TTC5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TTC5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 440 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TTC5

Target: TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))

Andere Bezeichnung: TTC5

Hintergrund: TTC5 is an adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. It is required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. It prevents p53/TP53 degradation by MDM2.
Alias Symbols: Strap
Protein Interaction Partner: AR, NR3C1, ESR1, CAMK2D, CAMK2B, UBC, CAND1, COPS5, CUL3, ELAVL1,
Protein Size: 440

Molekulargewicht: 49 kDa

Gen-ID: 91875

NCBI Accession: NM_138376, NP_612385

UniProt: Q8N0Z6

Pathways: Chromatin Binding