TGS1 Antikörper (Middle Region)

Produktnummer ABIN2783564

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TGS1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Meerschweinchen und Kaninchen.

Kurzübersicht für TGS1 Antikörper (Middle Region) (ABIN2783564)

Target: TGS1 (Trimethylguanosine Synthase 1 (TGS1))

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TGS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TGS1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: IDENPASDFD DSGSLLGFKY GSGQKYGGIP NFSHRQVRYL EKNVKLKSKY

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 93%, Horse: 85%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against TGS1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TGS1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 853 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TGS1

Target: TGS1 (Trimethylguanosine Synthase 1 (TGS1))

Andere Bezeichnung: TGS1

Hintergrund: TGS1 catalyzes the methylation step(s) for the conversion of the 7-monomethylguanosine (m7G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. TGS1 plays a role in transcriptional regulation.
Alias Symbols: DKFZp762A163, FLJ22995, NCOA6IP, PIMT, PIPMT
Protein Interaction Partner: LIN28A, UBC, COIL, Nhp2l1, NCOA6, HNF4A, EP300, EED, CREBBP, SNORD3A, MED1,
Protein Size: 853

Molekulargewicht: 96 kDa

Gen-ID: 96764

NCBI Accession: NM_024831, NP_079107

UniProt: Q96RS0

Pathways: Mitotic G1-G1/S Phases, Regulation of Lipid Metabolism by PPARalpha, Ribonucleoprotein Complex Subunit Organization