POLR1B Antikörper (Middle Region)

Produktnummer ABIN2783529

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch POLR1B in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Schwein, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen und Pferd.

Kurzübersicht für POLR1B Antikörper (Middle Region) (ABIN2783529)

Target: POLR1B (Polymerase (RNA) I Polypeptide B, 128kDa (POLR1B))

Reaktivität: Human, Maus, Ratte, Schwein, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLR1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-POLR1B Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: POLR1B Antibody - middle region

Sequenz: SDKFQVRTTG ARDRVTNQPI GGRNVQGGIR FGEMERDALL AHGTSFLLHD

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against POLR1B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human POLR1B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48848-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu POLR1B

Target: POLR1B (Polymerase (RNA) I Polypeptide B, 128kDa (POLR1B))

Andere Bezeichnung: POLR1B

Hintergrund:

Targeted Subunit: RPA2

Background Information: Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).

Gene Name: Polymerase (RNA) I polypeptide B, 128 kDa

Alternative Symbols: A135, RPA2, TCS4, RPA135, Rpo1-2

Protein Name: DNA-directed RNA polymerase I subunit RPA2

Molekulargewicht: 128kDa

Gen-ID: 84172

NCBI Accession: NP_061887

UniProt: Q9H9Y6