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HS2ST1 Antikörper (N-Term)

HS2ST1 Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2783487
  • Target Alle HS2ST1 Antikörper anzeigen
    HS2ST1 (Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1))
    Bindungsspezifität
    • 15
    • 10
    • 8
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 48
    • 20
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Pferd, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Schwein
    Wirt
    • 44
    • 4
    Kaninchen
    Klonalität
    • 47
    • 1
    Polyklonal
    Konjugat
    • 20
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HS2ST1 Antikörper ist unkonjugiert
    Applikation
    • 43
    • 21
    • 13
    • 13
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    GLLRIMMPPK LQLLAVVAFA VAMLFLENQI QKLEESRSKL ERAIARHEVR
    Homologie
    Cow: 77%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against HS2ST1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human HS2ST1
    Top Product
    Discover our top product HS2ST1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 356 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    HS2ST1 (Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1))
    Andere Bezeichnung
    HS2ST1 (HS2ST1 Produkte)
    Synonyme
    HS2ST1 antikoerper, hs2st antikoerper, dJ604K5.2 antikoerper, AW214369 antikoerper, Hs2st antikoerper, mKIAA0448 antikoerper, CHS2ST antikoerper, HS2ST antikoerper, 2-OST antikoerper, 2OST antikoerper, HS2st antikoerper, hs2st1 antikoerper, im:7147474 antikoerper, zgc:158230 antikoerper, heparan sulfate 2-O-sulfotransferase 1 antikoerper, Heparan sulfate 2-O-sulfotransferase 1 antikoerper, heparan sulfate 2-O-sulfotransferase 1 L homeolog antikoerper, heparan sulfate 2-O-sulfotransferase 1a antikoerper, HS2ST1 antikoerper, Tsp_05909 antikoerper, hs2st1 antikoerper, hs2st antikoerper, Hs2st1 antikoerper, hs2st1.L antikoerper, hs2st1a antikoerper
    Hintergrund
    Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. HS2ST1 is a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes heparan sulfate 2-O-sulfotransferase, a member of the heparan sulfate biosynthetic enzyme family. This family member transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation.
    Alias Symbols: FLJ11317, KIAA0448, MGC131986, dJ604K5.2
    Protein Size: 356
    Molekulargewicht
    42 kDa
    Gen-ID
    9653
    NCBI Accession
    NM_012262, NP_036394
    UniProt
    Q7LGA3
    Pathways
    Glycosaminoglycan Metabolic Process, Tube Formation, SARS-CoV-2 Protein Interaktom
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