STK3 Antikörper (N-Term)

Produktnummer ABIN2783468

Der Kaninchen-Polyklonal Anti-STK3-Antikörper wurde für WB validiert. Er ist geeignet zum Nachweis von STK3 in Proben aus Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Hund, Kaninchen, Pferd, Meerschweinchen und Schwein. }

Kurzübersicht für STK3 Antikörper (N-Term) (ABIN2783468)

Target: STK3 (serine/threonine Kinase 3 (STK3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Hund, Kaninchen, Pferd, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-STK3 Antikörper

Bindungsspezifität: N-Term

Sequenz: MEQPPAPKSK LKKLSEDSLT KQPEEVFDVL EKLGEGSYGS VFKAIHKESG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against STK3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human STK3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 491 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu STK3

Target: STK3 (serine/threonine Kinase 3 (STK3))

Andere Bezeichnung: STK3

Hintergrund: Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast 'sterile 20' (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand.Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast 'sterile 20' (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand (MIM 134638) (Taylor et al., 1996 [PubMed 8816758], Lee et al., 2001 [PubMed 11278283]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-11 U26424.1 1-11 12-2826 BC010640.2 1-2815
Alias Symbols: FLJ90748, KRS1, MST2
Protein Interaction Partner: RASSF2, SLMAP, TRAF1, GAD1, FAM9B, RASSF4, GMCL1, TFPT, FBXW11, UBC, AURKB, RAE1, YWHAB, TSPYL1, STRN, STK4, PRKRIR, PLK1, RASSF5, SAV1, CTTNBP2NL, MOB1A, MAP1S, STRN3, STRN4, LATS2, FGFR1OP2, MOB4, RASSF1, ERLIN2, KIF2C, RASSF3, RUNDC3B, MOB1B, STRIP1, S
Protein Size: 491

Molekulargewicht: 56 kDa

Gen-ID: 6788

NCBI Accession: NM_006281, NP_006272

UniProt: Q13188

Pathways: Tube Formation