STK3 Antikörper (N-Term)

Produktnummer ABIN2783468

Der Kaninchen Polyklonal Anti-STK3-Antikörper wurde für WB validiert. Er ist geeignet, STK3 in Proben von Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Hund, Kaninchen, Pferd, Meerschweinchen und Schwein zu detektieren.

Kurzübersicht für STK3 Antikörper (N-Term) (ABIN2783468)

Target: STK3 (serine/threonine Kinase 3 (STK3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Hund, Kaninchen, Pferd, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-STK3 Antikörper

Bindungsspezifität: N-Term

Sequenz: MEQPPAPKSK LKKLSEDSLT KQPEEVFDVL EKLGEGSYGS VFKAIHKESG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against STK3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human STK3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 491 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu STK3

Target: STK3 (serine/threonine Kinase 3 (STK3))

Andere Bezeichnung: STK3

Hintergrund: Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast 'sterile 20' (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand.Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast 'sterile 20' (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand (MIM 134638) (Taylor et al., 1996 [PubMed 8816758], Lee et al., 2001 [PubMed 11278283]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-11 U26424.1 1-11 12-2826 BC010640.2 1-2815
Alias Symbols: FLJ90748, KRS1, MST2
Protein Interaction Partner: RASSF2, SLMAP, TRAF1, GAD1, FAM9B, RASSF4, GMCL1, TFPT, FBXW11, UBC, AURKB, RAE1, YWHAB, TSPYL1, STRN, STK4, PRKRIR, PLK1, RASSF5, SAV1, CTTNBP2NL, MOB1A, MAP1S, STRN3, STRN4, LATS2, FGFR1OP2, MOB4, RASSF1, ERLIN2, KIF2C, RASSF3, RUNDC3B, MOB1B, STRIP1, S
Protein Size: 491

Molekulargewicht: 56 kDa

Gen-ID: 6788

NCBI Accession: NM_006281, NP_006272

UniProt: Q13188

Pathways: Tube Formation