SPTLC2 Antikörper (N-Term)

Produktnummer ABIN2783451

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch SPTLC2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio) und Pferd.

Kurzübersicht für SPTLC2 Antikörper (N-Term) (ABIN2783451)

Target: SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPTLC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SPTLC2 Antikörper

Bindungsspezifität: N-Term

Sequenz: VLTYVGYGVL TLFGYLRDFL RYWRIEKCHH ATEREEQKDF VSLYQDFENF

Homologie: Cow: 100%, Dog: 91%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SPTLC2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SPTLC2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 562 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SPTLC2

Target: SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))

Andere Bezeichnung: SPTLC2

Hintergrund: SPTLC2 is a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-973 AB011098.1 1-973 974-1108 BQ338973.1 306-440 1109-3679 AB011098.1 1109-3679 3680-4578 AB011098.1 3682-4580 4579-4876 BG024616.1 326-623 4877-6812 AB011098.1 4879-6814 6813-7189 W24363.1 55-431 7190-7250 BM992457.1 1-61 c
Alias Symbols: KIAA0526, LCB2, SPT2, HSN1C, LCB2A, NSAN1C, hLCB2a
Protein Interaction Partner: UBC, BCL6, SPTLC1,
Protein Size: 562

Molekulargewicht: 63 kDa

Gen-ID: 9517

NCBI Accession: NM_004863, NP_004854

UniProt: O15270