PAPSS2 Antikörper (C-Term)

Produktnummer ABIN2783448

Produktdetails anti-PAPSS2 Antikörper

Target: PAPSS2 (3'-phosphoadenosine 5'-phosphosulfate Synthase 2 (PAPSS2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAPSS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: PARHNEFDFI SGTRMRKLAR EGENPPDGFM APKAWKVLTD YYRSLEKN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PAPSS2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PAPSS2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 619 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PAPSS2 Antikörper (ABIN2783448)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Details zu PAPSS2

Target: PAPSS2 (3'-phosphoadenosine 5'-phosphosulfate Synthase 2 (PAPSS2))

Andere Bezeichnung: PAPSS2 (PAPSS2 Produkte)

Synonyme: ATPSK2 antikoerper, BCYM4 antikoerper, SK2 antikoerper, 1810018P12Rik antikoerper, AI159688 antikoerper, AtpsU2 antikoerper, Atpsk2 antikoerper, Sk2 antikoerper, bm antikoerper, Papss1 antikoerper, id:ibd2761 antikoerper, papss2 antikoerper, sb:cb868 antikoerper, wu:fb12e05 antikoerper, zgc:55851 antikoerper, zgc:85655 antikoerper, PAPSS2 antikoerper, zgc:153748 antikoerper, 3'-phosphoadenosine 5'-phosphosulfate synthase 2 antikoerper, 3'-phosphoadenosine 5'-phosphosulfate synthase 2b antikoerper, 3'-phosphoadenosine 5'-phosphosulfate synthase 2a antikoerper, PAPSS2 antikoerper, Papss2 antikoerper, papss2b antikoerper, papss2.S antikoerper, LOAG_05620 antikoerper, papss2 antikoerper, papss2a antikoerper

Hintergrund: Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. PAPSS2 is one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene.Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene.
Alias Symbols: ATPSK2, SK2
Protein Interaction Partner: RIC8A, ARIH2, GTF3C4, TXNRD1, TUBB2A, HNRNPA2B1, APEX1, UBD, UBC, APP, Papss1, VHL,
Protein Size: 619

Molekulargewicht: 70 kDa

Gen-ID: 9060

NCBI Accession: NM_001015880, NP_001015880

Pathways: Glycosaminoglycan Metabolic Process, Ribonucleoside Biosynthetic Process