Dnmt2 Antikörper (N-Term)
-
- Target Alle Dnmt2 (TRDMT1) Antikörper anzeigen
- Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))
-
Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Kaninchen, Meerschweinchen, Pferd
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser Dnmt2 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- MILMSPPCQP FTRIGRQGDM TDSRTNSFLH ILDILPRLQK LPKYILLENV
- Homologie
- Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TRDMT1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TRDMT1
- Top Product
- Discover our top product TRDMT1 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 391 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))
- Andere Bezeichnung
- TRDMT1 (TRDMT1 Produkte)
- Synonyme
- MGC89267 antikoerper, DMNT2 antikoerper, DNMT2 antikoerper, MHSAIIP antikoerper, PUMET antikoerper, RNMT1 antikoerper, Dnmt2 antikoerper, Rnmt2 antikoerper, dnmt2 antikoerper, tRNA aspartic acid methyltransferase 1 antikoerper, tRNA aspartic acid methyltransferase 1 L homeolog antikoerper, trdmt1 antikoerper, TRDMT1 antikoerper, Trdmt1 antikoerper, trdmt1.L antikoerper
- Hintergrund
-
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. TRDMT1 is a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome.CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: DNMT2, M.HsaIIP, PuMet, RNMT1, DMNT2, PUMET, MHSAIIP
Protein Interaction Partner: TBC1D2B, SNRPD3, NFRKB, GBE1, APP, LRIF1, COPS6, RBM48, SETDB1, UTP14A, DDX24, UNC119, STX1A, EEF1A1,
Protein Size: 391 - Molekulargewicht
- 44 kDa
- Gen-ID
- 1787
- NCBI Accession
- NM_004412, NP_004403
- UniProt
- O14717
-