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PYGB Antikörper (N-Term)

GPBB Reaktivität: Human, Maus, Ratte, Kaninchen, Schaf, Rind (Kuh), Zebrafisch (Danio rerio), Hund, Meerschweinchen, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2783431
  • Target Alle PYGB (GPBB) Antikörper anzeigen
    PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))
    Bindungsspezifität
    • 14
    • 8
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 46
    • 40
    • 23
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Kaninchen, Schaf, Rind (Kuh), Zebrafisch (Danio rerio), Hund, Meerschweinchen, Pferd
    Wirt
    • 57
    • 3
    Kaninchen
    Klonalität
    • 57
    • 3
    Polyklonal
    Konjugat
    • 28
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PYGB Antikörper ist unkonjugiert
    Applikation
    • 38
    • 28
    • 13
    • 10
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    QQHYYERDPK RIYYLSLEFY MGRTLQNTMV NLGLQNACDE AIYQLGLDLE
    Homologie
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 86%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PYGB. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human PYGB
    Top Product
    Discover our top product GPBB Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 843 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))
    Andere Bezeichnung
    PYGB (GPBB Produkte)
    Synonyme
    GPBB antikoerper, GLYPHOA antikoerper, glycogen phosphorylase B antikoerper, phosphorylase, glycogen; brain antikoerper, brain glycogen phosphorylase antikoerper, phosphorylase, glycogen; brain S homeolog antikoerper, PYGB antikoerper, pygb antikoerper, Pygb antikoerper, pygb.S antikoerper
    Hintergrund
    PYGB is a glycogen phosphorylase found predominantly in the brain. It forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MGC9213, GPBB
    Protein Interaction Partner: UBC, SIAH1, PYGL, PYGB, SUMO2, SUMO3, WDR61, RIC8A, OGFOD1, UBA6, UBR7, LIMD1, XPNPEP1, PLCG1, FH, NPM1, CPNE1, PSMB2, CAND1, SIRT7, MLH1, ACTN1,
    Protein Size: 843
    Molekulargewicht
    97 kDa
    Gen-ID
    5834
    NCBI Accession
    NM_002862, NP_002853
    UniProt
    P11216
    Pathways
    Cellular Glucan Metabolic Process
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