PYGB Antikörper (N-Term)

Produktnummer ABIN2783431

Der Kaninchen Polyklonal anti-PYGB Antikörper wird verwendet zum Nachweis von PYGB in Proben von Human, Maus, Ratte, Kaninchen, Schaf, Rind (Kuh), Zebrafisch (Danio rerio), Hund, Meerschweinchen und Pferd. Er wurde validiert für WB und IHC.

Kurzübersicht für PYGB Antikörper (N-Term) (ABIN2783431)

Target: PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))

Reaktivität: Human, Maus, Ratte, Kaninchen, Schaf, Rind (Kuh), Zebrafisch (Danio rerio), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PYGB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PYGB Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PYGB Antibody - N-terminal region

Sequenz: QQHYYERDPK RIYYLSLEFY MGRTLQNTMV NLGLQNACDE AIYQLGLDLE

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PYGB. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PYGB

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48586-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PYGB

Target: PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))

Andere Bezeichnung: PYGB

Hintergrund:

Background Information: PYGB is a glycogen phosphorylase found predominantly in the brain. It forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Phosphorylase, glycogen, brain

Alternative Symbols: GPBB

Protein Name: Glycogen phosphorylase, brain form

Molekulargewicht: 97 kDa

Gen-ID: 5834

NCBI Accession: NP_002853

UniProt: P11216

Pathways: Cellular Glucan Metabolic Process