GATM Antikörper (Middle Region)

Produktnummer ABIN2783416

Der Kaninchen Polyklonal anti-GATM Antikörper wird verwendet zum Nachweis von GATM in Proben von Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh), Kaninchen, Schaf und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für GATM Antikörper (Middle Region) (ABIN2783416)

Target: GATM (Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh), Kaninchen, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GATM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GATM Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: GATM Antibody - middle region

Sequenz: PCFDAADFIR AGRDIFAQRS QVTNYLGIEW MRRHLAPDYR VHIISFKDPN

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against GATM. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GATM

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48553-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GATM

Target: GATM (Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM))

Andere Bezeichnung: GATM

Hintergrund:

Background Information: GATM is a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Glycine amidinotransferase (L-arginine:glycine amidinotransferase)

Alternative Symbols: AT, AGAT, CCDS3, FRTS1

Protein Name: Glycine amidinotransferase, mitochondrial

Molekulargewicht: 48 kDa

Gen-ID: 2628

NCBI Accession: NP_001473

UniProt: P50440