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FNTA Antikörper (C-Term)

Dieses Anti-FNTA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FNTA in WB. Geeignet für Human, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Schwein und Schaf.
Produktnummer ABIN2783403

Kurzübersicht für FNTA Antikörper (C-Term) (ABIN2783403)

Target

Alle FNTA Antikörper anzeigen
FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Reaktivität

Human, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Schwein, Schaf

Wirt

  • 44
  • 3
Kaninchen

Klonalität

  • 45
  • 2
Polyklonal

Konjugat

  • 22
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FNTA Antikörper ist unkonjugiert

Applikation

  • 40
  • 13
  • 13
  • 7
  • 6
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    DNKEDILNKA LELCEILAKE KDTIRKEYWR YIGRSLQSKH STENDSPTNV

    Homologie

    Cow: 92%, Dog: 92%, Horse: 92%, Human: 100%, Pig: 92%, Rabbit: 100%, Rat: 92%, Sheep: 92%

    Produktmerkmale

    This is a rabbit polyclonal antibody against FNTA. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Protein A purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C terminal region of human FNTA
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 312 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

    Andere Bezeichnung

    FNTA

    Hintergrund

    Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. FNTA is the alpha subunit of these transferases.Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Alias Symbols: FPTA, MGC99680, PGGT1A, PTAR2
    Protein Interaction Partner: UBC, HK2, DYRK1A, RPL13A, SAFB2, TGM2, STAT2, INHBB, VAV2, HDAC6, PTP4A3, GBP1, CENPF, TGFBR1, TGFB1, KRAS, HRAS, RHOB, FNTB, ACVR1, PTP4A2,
    Protein Size: 312

    Molekulargewicht

    36 kDa

    Gen-ID

    2339

    NCBI Accession

    NM_001018677, NP_001018197

    UniProt

    A6NJW0

    Pathways

    Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling
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