FNTA Antikörper (C-Term)

Produktnummer ABIN2783403

Produktdetails anti-FNTA Antikörper

Target: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Schwein, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FNTA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DNKEDILNKA LELCEILAKE KDTIRKEYWR YIGRSLQSKH STENDSPTNV

Homologie: Cow: 92%, Dog: 92%, Horse: 92%, Human: 100%, Pig: 92%, Rabbit: 100%, Rat: 92%, Sheep: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against FNTA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FNTA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 312 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FNTA

Target: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Andere Bezeichnung: FNTA (FNTA Produkte)

Hintergrund: Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. FNTA is the alpha subunit of these transferases.Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: FPTA, MGC99680, PGGT1A, PTAR2
Protein Interaction Partner: UBC, HK2, DYRK1A, RPL13A, SAFB2, TGM2, STAT2, INHBB, VAV2, HDAC6, PTP4A3, GBP1, CENPF, TGFBR1, TGFB1, KRAS, HRAS, RHOB, FNTB, ACVR1, PTP4A2,
Protein Size: 312

Molekulargewicht: 36 kDa

Gen-ID: 2339

NCBI Accession: NM_001018677, NP_001018197

UniProt: A6NJW0

Pathways: Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling