GSTA3 Antikörper (Middle Region)

Produktnummer ABIN2783389

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GSTA3 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Schaf.

Kurzübersicht für GSTA3 Antikörper (Middle Region) (ABIN2783389)

Target: GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))

Reaktivität: Human, Maus, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSTA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GSTA3 Antikörper

Bindungsspezifität: Middle Region

Sequenz: SSLISNFPLL KALKTRISNL PTVKKFLQPG SPRKPPADAK ALEEARKIFR

Homologie: Human: 100%, Mouse: 79%, Sheep: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against GSTA3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GSTA3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 222 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GSTA3

Target: GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))

Andere Bezeichnung: GSTA3

Hintergrund: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined.
Alias Symbols: GSTA3-3, GTA3, MGC22232
Protein Interaction Partner: BAG3, APP,
Protein Size: 222

Molekulargewicht: 25 kDa

Gen-ID: 2940

NCBI Accession: NM_000847, NP_000838

UniProt: Q16772