OXCT1 Antikörper (Middle Region)
Kurzübersicht für OXCT1 Antikörper (Middle Region) (ABIN2783388)
Target
Alle OXCT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- GMYANLGIGI PLLASNFISP NITVHLQSEN GVLGLGPYPR QHEADADLIN
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Homologie
- Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 92%
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Produktmerkmale
- This is a rabbit polyclonal antibody against OXCT1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human OXCT1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 520 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- OXCT1 (3-Oxoacid CoA Transferase 1 (OXCT1))
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Andere Bezeichnung
- OXCT1
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Hintergrund
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CT1 is a member of the 3-oxoacid CoA-transferase gene family. It is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate.This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.
Alias Symbols: OXCT, SCOT
Protein Interaction Partner: SUMO2, UBC, MDM2, THOP1, RBBP7, PTPN11, PTMS, NME1, IDH1, HSPD1, MAPK14, ADSS, MTPN, C12orf10, CBX3, C11orf58, WDR1, IQCB1, TMEM189, TMEM9, VMA21, S100A16, TMEM177, SCAF4, SEPT11, SDHAF2, TIMM9, TOR1AIP1, UBXN7, VAPB, SUCLA2, SUCLG1, UQCRFS1P1, UQCRFS1, T
Protein Size: 520 -
Molekulargewicht
- 52 kDa
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Gen-ID
- 5019
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NCBI Accession
- NM_000436, NP_000427
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UniProt
- P55809
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Pathways
- Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
Target
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