Hsc70 Antikörper (N-Term)

Produktnummer ABIN2783374

Der Kaninchen Polyklonal Anti-Hsc70-Antikörper wurde für WB und IHC validiert. Er ist geeignet, Hsc70 in Proben von Human, Ratte, Maus, Rind (Kuh), Schaf, Schwein, Zebrafisch (Danio rerio) und Ziege zu detektieren.

Kurzübersicht für Hsc70 Antikörper (N-Term) (ABIN2783374)

Target: Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Schaf, Schwein, Zebrafisch (Danio rerio), Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Hsc70 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Hsc70 Antikörper

Bindungsspezifität: N-Term

Sequenz: MSKGPAVGID LGTTYSCVGV FQHGKVEIIA NDQGNRTTPS YVAFTDTERL

Homologie: Cow: 100%, Goat: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HSPA8. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HSPA8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 646 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Hsc70

Target: Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

Andere Bezeichnung: HSPA8

Hintergrund: HSPA8 belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. HSPA8 is a heat-shock cognate protein. The protein binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Two alternatively spliced variants have been characterized to date.The product encoded by this gene belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This gene encodes a heat-shock cognate protein. This protein binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Two alternatively spliced variants have been characterized to date.
Alias Symbols: HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, LAP1, MGC131511, MGC29929, NIP71
Protein Interaction Partner: FUS, HSPBP1, TRIM38, STUB1, ISG15, UBC, TP53, BAG1, BAG3, IL32, NMI, AIRE, HAUS2, TUBGCP4, CEP250, TUBGCP2, TUBGCP3, TUBG1, AURKA, SUMO2, SUMO3, MDM2, LGALS3BP, CDKN1A, CDC20, HAUS1, STAU1, ST13, HSPA4, HSPA2, DNAJA1, GABRB1, EDRF1, DNAJC9, HSPA4L, HSPH1,
Protein Size: 646

Molekulargewicht: 71 kDa

Gen-ID: 3312

NCBI Accession: NM_006597, NP_006588

UniProt: P11142