GRHPR Antikörper (N-Term)

Produktnummer ABIN2783330

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GRHPR in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Ratte, Hund, Schwein, Pferd und Kaninchen und wurde in 1 Publikation erwähnt.

Kurzübersicht für GRHPR Antikörper (N-Term) (ABIN2783330)

Target: GRHPR (Glyoxylate Reductase/hydroxypyruvate Reductase (GRHPR))

Reaktivität: Human, Ratte, Hund, Schwein, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRHPR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-GRHPR Antikörper

Bindungsspezifität: N-Term

Sequenz: EPIPAKELER GVAGAHGLLC LLSDHVDKRI LDAAGANLKV ISTMSVGIDH

Homologie: Dog: 100%, Horse: 86%, Human: 100%, Pig: 79%, Rabbit: 93%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against GRHPR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GRHPR

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 328 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-GRHPR Antikörper (ABIN2783330)

Takayama, Nagata, Ozono, Nonomura, Cramer: "A novel mutation in the GRHPR gene in a Japanese patient with primary hyperoxaluria type 2." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 22, Issue 8, pp. 2371-4, (2007) (PubMed).

Details zu GRHPR

Target: GRHPR (Glyoxylate Reductase/hydroxypyruvate Reductase (GRHPR))

Andere Bezeichnung: GRHPR

Hintergrund: GRHPR is an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene.This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GLXR, PH2, GLYD
Protein Interaction Partner: GLS2, CDC7, UBC, PTH2R, FOS, LIG4, SUCLA2, PGM1, HSD17B4, CXADR, SLC25A5, ACOX1, LSM1,
Protein Size: 328

Molekulargewicht: 36 kDa

Gen-ID: 9380

NCBI Accession: NM_012203, NP_036335

UniProt: Q9UBQ7