Selenoprotein F Antikörper (C-Term)

Produktnummer ABIN2783301

Der Kaninchen Polyklonal anti-Selenoprotein F Antikörper wird verwendet zum Nachweis von Selenoprotein F in Proben von Rind (Kuh), Human, Maus, Schwein, Ratte und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für Selenoprotein F Antikörper (C-Term) (ABIN2783301)

Target: Selenoprotein F (SELENOF)

Reaktivität: Rind (Kuh), Human, Maus, Schwein, Ratte, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Selenoprotein F Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Selenoprotein F Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: SELENOF Antibody - C-terminal region

Sequenz: LFRGLQIKYV RGSDPVLKLL DDNGNIAEEL SILKWNTDSV EEFLSEKLER

Homologie: Cow: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against sep15. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Rat sep15

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48248-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Selenoprotein F

Target: Selenoprotein F (SELENOF)

Andere Bezeichnung: SELENOF

Hintergrund:

Background Information: The protein encoded by this gene belongs to the SEP15/selenoprotein M family. The exact function of this protein is not known; however, it has been found to associate with UDP-glucose:glycoprotein glucosyltransferase (UGTR), an endoplasmic reticulum(ER)-resident protein, which is involved in the quality control of protein folding. The association with UGTR retains this protein in the ER, where it may play a role in protein folding. Knockout studies in mice also suggest a role for this gene in cataract formation and colon carcinogenesis. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal.

Gene Name: selenoprotein F

Alternative Symbols: 45184

Protein Name: selenoprotein F

Molekulargewicht: 17kDa

Gen-ID: 113922

NCBI Accession: NP_579831

UniProt: Q923V8