TCAP Antikörper (N-Term)

Produktnummer ABIN2783290

Der Kaninchen Polyklonal anti-TCAP Antikörper (ABIN2783290) detektiert spezifisch TCAP in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Ziege.

Kurzübersicht für TCAP Antikörper (N-Term) (ABIN2783290)

Target: TCAP (Titin-Cap (Telethonin) (TCAP))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TCAP Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: TCAP Antibody - N-terminal region

Sequenz: CSLHEEDTQR HETYHQQGQC QVLVQRSPWL MMRMGILGRG LQEYQLPYQR

Homologie: Cow: 100%, Dog: 93%, Goat: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TCAP. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TCAP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48227-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TCAP

Target: TCAP (Titin-Cap (Telethonin) (TCAP))

Andere Bezeichnung: TCAP

Hintergrund:

Background Information: Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Titin-cap (telethonin)

Alternative Symbols: TELE, CMD1N, CMH25, T-cap, LGMD2G, LGMDR7, telethonin

Protein Name: Telethonin

Molekulargewicht: 19kDa

Gen-ID: 8557

NCBI Accession: NP_003664

UniProt: O15273