Tropomyosin-2 (TPM2) (C-Term) Antikörper

Details zu Produkt Nr. ABIN2783288, Anbieter: Anmelden zum Anzeigen
Antigen
  • CG4843
  • DROTROPI1
  • Dmel\\CG4843
  • Ifm(3)3
  • Ifm(3)5
  • Ifm-TmI
  • TM2
  • Tm
  • Tm1
  • Tm127
  • TmI
  • TmII
  • Tn-H
  • dro Tm
  • l(3)nc99Eb
  • mTmI
  • cb836
  • fb68h02
  • tpm4l
  • wu:fb68h02
  • wu:fj63f03
  • zgc:86810
  • AMCD1
  • DA1
  • DA2B
  • TMSB
  • nem4
  • tpm2
  • tpm2a
  • BRT-2
  • TPM3
  • NEM4
  • Tpm-2
  • Trop-2
  • Tropomyosin 2
  • Tropomyosin-2
  • tropomyosin
  • tropomyosin 2 (beta)
  • tropomyosin 2 L homeolog
  • tropomyosin 2
  • tropomyosin 2, beta
  • Tm2
  • EDI_309330
  • LOC100101174
  • tpm2
  • tpm2.L
  • TPM2
  • Tpm2
Epitop
C-Term
12
9
8
3
2
2
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Schaf, Zebrafisch (Danio rerio)
67
21
17
6
2
1
1
1
1
1
Wirt
Kaninchen
59
8
Klonalität
Polyklonal
Konjugat
Unkonjugiert
5
5
5
2
2
2
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
60
36
21
9
3
2
2
2
1
Optionen
Hersteller
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Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human TPM2
Sequenz AETRAEFAER SVAKLEKTID DLEDEVYAQK MKYKAISEEL DNALNDITSL
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 100%, Pig: 85%, Rabbit: 100%, Rat: 100%, Sheep: 85%, Zebrafish: 86%
Produktmerkmale This is a rabbit polyclonal antibody against TPM2. It was validated on Western Blot and immunohistochemistry.
Reinigung Protein A purified
Andere Bezeichnung TPM2 (TPM2 Antibody Abstract)
Hintergrund TPM2 is beta-tropomyosin, an isoform of tropomyosin that is mainly expressed in slow, type 1 muscle fibers.The TPM2 gene encodes beta-tropomyosin, an isoform of tropomyosin that is mainly expressed in slow, type 1 muscle fibers (Tajsharghi et al., 2007 [PubMed 17846275]). See also TPM1 (MIM 191010), TPM3 (MIM 191030), and TPM4 (MIM 600317).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AMCD1, DA1, TMSB, DA2B, NEM4
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, HECTD1, SKIL, STAM, TPM4, TPM3, TPM1, SULT1A1, NONO, STMN1, DYNC1H1, DDX3X, DDB1, SRXN1, CPSF7, CORO1B, DSTN, SF3B2, AHCYL1, DDX46, TAF15, LRRK2, AKT1, SP1, ACTA1, S100A4, TPM2, PDLIM7, PIK3CG, RRAD, S100A2, JUN, ADRBK1, ACTB,
Protein Size: 284
Molekulargewicht 33 kDa
Gen-ID 7169
NCBI Accession NM_003289, NP_003280
UniProt P07951
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 284 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Tropomyosin-2 (TPM2) (C-Term) antibody (ABIN2783288) anti-Tropomyosin-2 (TPM2) (C-Term) antibody
Produkt verwendet in: Abdul-Hussein, Rahl, Moslemi, Tajsharghi: "Phenotypes of myopathy-related beta-tropomyosin mutants in human and mouse tissue cultures." in: PLoS ONE, Vol. 8, Issue 9, pp. e72396, 2013 (PubMed).

Tajsharghi, Ohlsson, Lindberg, Oldfors: "Congenital myopathy with nemaline rods and cap structures caused by a mutation in the beta-tropomyosin gene (TPM2)." in: Archives of neurology, Vol. 64, Issue 9, pp. 1334-8, 2007 (PubMed).

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