TPM2 Antikörper (C-Term)

Produktnummer ABIN2783288

Dieses Anti-TPM2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TPM2 in WB und IHC. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Schwein und Schaf. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für TPM2 Antikörper (C-Term) (ABIN2783288)

Target: TPM2 (Tropomyosin-2 (TPM2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Schwein, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TPM2 Antikörper

Bindungsspezifität: C-Term

Sequenz: AETRAEFAER SVAKLEKTID DLEDEVYAQK MKYKAISEEL DNALNDITSL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 100%, Pig: 85%, Rabbit: 100%, Rat: 100%, Sheep: 85%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against TPM2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TPM2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 284 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TPM2 Antikörper (ABIN2783288)

Abdul-Hussein, Rahl, Moslemi, Tajsharghi: "Phenotypes of myopathy-related beta-tropomyosin mutants in human and mouse tissue cultures." in: PLoS ONE, Vol. 8, Issue 9, pp. e72396, (2013) (PubMed).

Tajsharghi, Ohlsson, Lindberg, Oldfors: "Congenital myopathy with nemaline rods and cap structures caused by a mutation in the beta-tropomyosin gene (TPM2)." in: Archives of neurology, Vol. 64, Issue 9, pp. 1334-8, (2007) (PubMed).

Details zu TPM2

Target: TPM2 (Tropomyosin-2 (TPM2))

Andere Bezeichnung: TPM2

Hintergrund: TPM2 is beta-tropomyosin, an isoform of tropomyosin that is mainly expressed in slow, type 1 muscle fibers.The TPM2 gene encodes beta-tropomyosin, an isoform of tropomyosin that is mainly expressed in slow, type 1 muscle fibers (Tajsharghi et al., 2007 [PubMed 17846275]). See also TPM1 (MIM 191010), TPM3 (MIM 191030), and TPM4 (MIM 600317).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AMCD1, DA1, TMSB, DA2B, NEM4
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, HECTD1, SKIL, STAM, TPM4, TPM3, TPM1, SULT1A1, NONO, STMN1, DYNC1H1, DDX3X, DDB1, SRXN1, CPSF7, CORO1B, DSTN, SF3B2, AHCYL1, DDX46, TAF15, LRRK2, AKT1, SP1, ACTA1, S100A4, TPM2, PDLIM7, PIK3CG, RRAD, S100A2, JUN, ADRBK1, ACTB,
Protein Size: 284

Molekulargewicht: 33 kDa

Gen-ID: 7169

NCBI Accession: NM_003289, NP_003280

UniProt: P07951