CRYAB Antikörper (C-Term)

Produktnummer ABIN2783274

Der Kaninchen Polyklonal anti-CRYAB Antikörper wird verwendet zum Nachweis von CRYAB in Proben von Human, Ratte, Maus, Rind (Kuh), Schaf, Hund, Meerschweinchen, Kaninchen und Pferd. Er wurde validiert für WB.

Kurzübersicht für CRYAB Antikörper (C-Term) (ABIN2783274)

Target: CRYAB (Crystallin, alpha B (CRYAB))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Schaf, Hund, Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRYAB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CRYAB Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: CRYAB Antibody - C-terminal region

Sequenz: KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVT

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against CRYAB. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CRYAB

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48196-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CRYAB

Target: CRYAB (Crystallin, alpha B (CRYAB))

Andere Bezeichnung: CRYAB

Hintergrund:

Background Information: Alpha crystallins are composed of: alpha-A and alpha-B, for acidic and basic, respectively. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases, a missense mutation cosegregated in a family with a desmin-related myopathy.

Gene Name: Crystallin, alpha B

Alternative Symbols: MFM2, CRYA2, CTPP2, HSPB5, CMD1II, CTRCT16, HEL-S-101

Protein Name: Alpha-crystallin B chain

Molekulargewicht: 20kDa

Gen-ID: 1410

UniProt: P02511