GBAS Antikörper (Middle Region)

Produktnummer ABIN2783257

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GBAS in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd und Zebrafisch (Danio rerio) und wurde in 1 Publikation erwähnt.

Kurzübersicht für GBAS Antikörper (Middle Region) (ABIN2783257)

Target: GBAS (Glioblastoma Amplified Sequence (GBAS))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GBAS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GBAS Antikörper

Bindungsspezifität: Middle Region

Sequenz: VPRSGPNIYE LRSYQLRPGT MIEWGNYWAR AIRFRQDGNE AVGGFFSQIG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against GBAS. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GBAS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 286 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-GBAS Antikörper (ABIN2783257)

Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

Details zu GBAS

Target: GBAS (Glioblastoma Amplified Sequence (GBAS))

Andere Bezeichnung: GBAS

Hintergrund: Chromosomal region 7p12, which contains GBAS, is amplified in approximately 40 % of glioblastomas, the most common and malignant form of central nervous system tumor.The predicted 286-amino acid protein contains a signal peptide, a transmembrane domain, and 2 tyrosine phosphorylation sites. The GBAS transcript is expressed most abundantly in heart and skeletal muscle. GBAS protein might be involved in vesicular transport.Chromosomal region 7p12, which contains GBAS, is amplified in approximately 40 % of glioblastomas, the most common and malignant form of central nervous system tumor.The predicted 286-amino acid protein contains a signal peptide, a transmembrane domain, and 2 tyrosine phosphorylation sites. The GBAS transcript is expressed most abundantly in heart and skeletal muscle. GBAS protein might be involved in vesicular transport.
Alias Symbols: NIPSNAP2
Protein Interaction Partner: VCP, UBC, SUMO1, NEDD8, AMOT, CDH1, CUL3, EBNA-LP, PRKCI, MAP1LC3A, MAP1LC3B, LARS, ANKFY1, GABARAPL1, GANAB, GABARAPL2, GABARAP, DDX39A, NAMPT, NPEPPS, LONP1, MTA2, SQSTM1, NIPSNAP1, WARS, TARS, PRKDC, PGK1, PFKP, PFAS, PA2G4, HK1, HADHA, FOXO3, FKBP4, A
Protein Size: 286

Molekulargewicht: 34 kDa

Gen-ID: 2631

NCBI Accession: NM_001483, NP_001474

UniProt: O75323

Pathways: Ribonucleoside Biosynthetic Process