ALDOA Antikörper (N-Term)

Produktnummer ABIN2783231

Zitiert in 2+ Publikationen. Der Kaninchen Polyklonal anti-ALDOA Antikörper (ABIN2783231) detektiert spezifisch ALDOA in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Pferd, Schaf und Zebrafisch (Danio rerio).

Kurzübersicht für ALDOA Antikörper (N-Term) (ABIN2783231)

Target: ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Pferd, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALDOA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ALDOA Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: ALDOA Antibody - N-terminal region

Sequenz: MPYQYPALTP EQKKELSDIA HRIVAPGKGI LAADESTGSI AKRLQSIGTE

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 93%, Sheep: 82%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against ALDOA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ALDOA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48130-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ALDOA Antikörper (ABIN2783231)

Braceland, McLoughlin, Tinsley, Wallace, Cockerill, McLaughlin, Eckersall: "Serum enolase: a non-destructive biomarker of white skeletal myopathy during pancreas disease (PD) in Atlantic salmon Salmo salar L." in: Journal of fish diseases, Vol. 38, Issue 9, pp. 821-31, (2015) (PubMed).

Mao, Yang, Xu, Sang, Lu, Yang, Zhang, Zhong, Huang, Zhang: "[Significance of Golgi glycoprotein 73, a new tumor marker in diagnosis of hepatocellular carcinoma: a primary study]." in: Zhonghua yi xue za zhi, Vol. 88, Issue 14, pp. 948-51, (2008) (PubMed).

Details zu ALDOA

Target: ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))

Andere Bezeichnung: ALDOA

Hintergrund:

Background Information: ALDOA is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia.This gene product, Aldolase A (fructose-bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants which encode the same protein.

Gene Name: Aldolase A, fructose-bisphosphate

Alternative Symbols: ALDA, GSD12, HEL-S-87p

Protein Name: Fructose-bisphosphate aldolase A

Molekulargewicht: 39 kDa

Gen-ID: 226

NCBI Accession: NP_000025

UniProt: P04075

Pathways: Ribonucleoside Biosynthetic Process