ALDOA Antikörper (N-Term)

Produktnummer ABIN2783231

Dieser Anti-ALDOA Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von ALDOA in WB. Geeignet für Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio) und Schaf. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für ALDOA Antikörper (N-Term) (ABIN2783231)

Target: ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALDOA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ALDOA Antikörper

Bindungsspezifität: N-Term

Sequenz: MPYQYPALTP EQKKELSDIA HRIVAPGKGI LAADESTGSI AKRLQSIGTE

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 93%, Sheep: 82%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against ALDOA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ALDOA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 364 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ALDOA Antikörper (ABIN2783231)

Braceland, McLoughlin, Tinsley, Wallace, Cockerill, McLaughlin, Eckersall: "Serum enolase: a non-destructive biomarker of white skeletal myopathy during pancreas disease (PD) in Atlantic salmon Salmo salar L." in: Journal of fish diseases, Vol. 38, Issue 9, pp. 821-31, (2015) (PubMed).

Mao, Yang, Xu, Sang, Lu, Yang, Zhang, Zhong, Huang, Zhang: "[Significance of Golgi glycoprotein 73, a new tumor marker in diagnosis of hepatocellular carcinoma: a primary study]." in: Zhonghua yi xue za zhi, Vol. 88, Issue 14, pp. 948-51, (2008) (PubMed).

Details zu ALDOA

Target: ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))

Andere Bezeichnung: ALDOA

Hintergrund: ALDOA is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia.This gene product, Aldolase A (fructose-bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants which encode the same protein.
Alias Symbols: ALDA, MGC10942, MGC17716, MGC17767, GSD12
Protein Interaction Partner: HUWE1, UBC, IFNA4, FUS, ALDOC, ALDOA, SUMO2, SUMO3, MDM2, ADRB2, SUZ12, TNPO3, CS, RAD52, VCPKMT, PIAS4, GALNT6, IQCB1, VCAM1, MLH1, ITGA4, HSP90AB1, HSP90AA1, FN1, ATF2, BCAT2, ALDOB, LIG4, PGK1, LGALS1, HSPD1, AKT1, MYOC, CDK2, CUL2, CUL3, CUL4B, ISG15,
Protein Size: 364

Molekulargewicht: 39 kDa

Gen-ID: 226

NCBI Accession: NM_000034, NP_000025

UniProt: P04075

Pathways: Ribonucleoside Biosynthetic Process