SGSH Antikörper (C-Term)

Produktnummer ABIN2783228

Der Kaninchen Polyklonal anti-SGSH Antikörper wird verwendet zum Nachweis von SGSH in Proben von Human, Maus, Ratte, Rind (Kuh), Pferd und Hund. Er wurde validiert für WB.

Kurzübersicht für SGSH Antikörper (C-Term) (ABIN2783228)

Target: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SGSH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SGSH Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: SGSH Antibody - C-terminal region

Sequenz: ARWELYDRSR DPHETQNLAT DPRFAQLLEM LRDQLAKWQW ETHDPWVCAP

Homologie: Cow: 79%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SGSH. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human SGSH

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48124-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SGSH

Target: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Andere Bezeichnung: SGSH

Hintergrund:

Background Information: This gene encodes one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined.

Gene Name: N-sulfoglucosamine sulfohydrolase

Alternative Symbols: HSS, SFMD, MPS3A

Protein Name: N-sulphoglucosamine sulphohydrolase

Molekulargewicht: 32kDa

Gen-ID: 6448

NCBI Accession: NP_000190

UniProt: P51688

Pathways: Glycosaminoglycan Metabolic Process