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PAX8 Antikörper (N-Term)

PAX8 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2783221
  • Target Alle PAX8 Antikörper anzeigen
    PAX8 (Paired Box 8 (PAX8))
    Bindungsspezifität
    • 28
    • 11
    • 9
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 111
    • 47
    • 44
    • 19
    • 19
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)
    Wirt
    • 72
    • 38
    • 1
    Kaninchen
    Klonalität
    • 56
    • 55
    Polyklonal
    Konjugat
    • 62
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PAX8 Antikörper ist unkonjugiert
    Applikation
    • 87
    • 36
    • 31
    • 30
    • 26
    • 17
    • 16
    • 12
    • 11
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    KSLSPGHTLI PSSAVTPPES PQSDSLGSTY SINGLLGIAQ PGSDKRKMDD
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PAX8. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human PAX8
    Top Product
    Discover our top product PAX8 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 450 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

  • Target
    PAX8 (Paired Box 8 (PAX8))
    Andere Bezeichnung
    PAX8 (PAX8 Produkte)
    Synonyme
    PAX8 antikoerper, XPax-8 antikoerper, XPax8 antikoerper, pax-8 antikoerper, PAX-8 antikoerper, Pax-8 antikoerper, paired box 8 antikoerper, paired box 8 L homeolog antikoerper, PAX8 antikoerper, pax8 antikoerper, Pax8 antikoerper, pax8.L antikoerper
    Hintergrund
    PAX8 is a member of the paired box (PAX) family of transcription factors. Members of this family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in its gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas.This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins which contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Alias Symbols: -
    Protein Interaction Partner: SERINC1, ANXA7, PKM, CXCL9, CHUK, POU2AF1, WBP2, SMAD3, EP300, NKX2-1, ID2,
    Protein Size: 450
    Molekulargewicht
    48 kDa
    Gen-ID
    7849
    NCBI Accession
    NM_003466, NP_003457
    UniProt
    Q06710
    Pathways
    Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation
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