Myosin 9 Antikörper (Middle Region)

Produktnummer ABIN2783216

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-Myosin 9 Antikörper wird verwendet zum Nachweis von Myosin 9 in Proben von Human, Maus, Ratte, Hund, Schwein, Meerschweinchen und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für Myosin 9 Antikörper (Middle Region) (ABIN2783216)

Target: Myosin 9 (MYH9)

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Myosin 9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Myosin 9 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: MYH9 Antibody - middle region

Sequenz: DAMNREVSSL KNKLRRGDLP FVVPRRMARK GAGDGSDEEV DGKADGAEAK

Homologie: Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against MYH9. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MYH9

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48072-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Myosin 9 Antikörper (ABIN2783216)

Sabbir, Dillon, Mowat: "Dlc1 interaction with non-muscle myosin heavy chain II-A (Myh9) and Rac1 activation." in: Biology open, Vol. 5, Issue 4, pp. 452-60, (2016) (PubMed).

Details zu Myosin 9

Target: Myosin 9 (MYH9)

Andere Bezeichnung: MYH9

Hintergrund:

Background Information: MYH9 is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.

Gene Name: Myosin, heavy chain 9, non-muscle

Alternative Symbols: MHA, FTNS, EPSTS, BDPLT6, DFNA17, MATINS, NMMHCA, NMHC-II-A, NMMHC-IIA

Protein Name: Myosin-9

Molekulargewicht: 226kDa

Gen-ID: 4627

NCBI Accession: NP_002464

UniProt: P35579

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Integrin Complex