PHF5A Antikörper (Middle Region)
Kurzübersicht für PHF5A Antikörper (Middle Region) (ABIN2783095)
Target
Alle PHF5A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- ICGGPGVSDA YYCKECTIQE KDRDGCPKIV NLGSSKTDLF YERKKYGFKK
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Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PHF5A. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PHF5A
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 110 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PHF5A (PHD Finger Protein 5A (PHF5A))
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Andere Bezeichnung
- PHF5A
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Hintergrund
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This gene encodes a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein. This gene has several pseudogenes on different chromosomes.
Alias Symbols: INI, MGC1346, SF3b14b, bK223H9.2, Rds3, SAP14b
Protein Interaction Partner: UBC, EZH2, BMI1, SUZ12, RNF2, SRPK3, FOXB1, PRPF31, SF3B5, RBM25, SF3B6, SF3B1, SF3B3, SF3B2, SF3B4, DDX23, SNRPB2, SNRPA1, SFPQ, S100A10, YBX1, NCL, HNRNPA1, DHX8, SF3A2, Sf3a1, SUMO2, RNU11, RNU12-2P,
Protein Size: 110 -
Molekulargewicht
- 12 kDa
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Gen-ID
- 84844
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NCBI Accession
- NM_032758, NP_116147
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UniProt
- Q7RTV0
Target
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