PHF5A Antikörper (Middle Region)

Produktnummer ABIN2783095

Produktdetails anti-PHF5A Antikörper

Target: PHF5A (PHD Finger Protein 5A (PHF5A))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHF5A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ICGGPGVSDA YYCKECTIQE KDRDGCPKIV NLGSSKTDLF YERKKYGFKK

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PHF5A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PHF5A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 110 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PHF5A

Target: PHF5A (PHD Finger Protein 5A (PHF5A))

Andere Bezeichnung: PHF5A (PHF5A Produkte)

Hintergrund: This gene encodes a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein. This gene has several pseudogenes on different chromosomes.
Alias Symbols: INI, MGC1346, SF3b14b, bK223H9.2, Rds3, SAP14b
Protein Interaction Partner: UBC, EZH2, BMI1, SUZ12, RNF2, SRPK3, FOXB1, PRPF31, SF3B5, RBM25, SF3B6, SF3B1, SF3B3, SF3B2, SF3B4, DDX23, SNRPB2, SNRPA1, SFPQ, S100A10, YBX1, NCL, HNRNPA1, DHX8, SF3A2, Sf3a1, SUMO2, RNU11, RNU12-2P,
Protein Size: 110

Molekulargewicht: 12 kDa

Gen-ID: 84844

NCBI Accession: NM_032758, NP_116147

UniProt: Q7RTV0