MTA3 Antikörper (C-Term)
Kurzübersicht für MTA3 Antikörper (C-Term) (ABIN2783072)
Target
Alle MTA3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- TTEDPRVRSH VSRQAMQGMP VRNTGSPKSA VKTRQAFFLH TTYFTKFARQ
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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Produktmerkmale
- This is a rabbit polyclonal antibody against MTA3. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human MTA3
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 515 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MTA3 (Metastasis Associated 1 Family, Member 3 (MTA3))
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Andere Bezeichnung
- MTA3
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Hintergrund
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MTA3 plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels.
Alias Symbols: KIAA1266
Protein Interaction Partner: BCL6, NACC2, UBC, HNRNPA2B1, SOX2, HDAC2, HDAC1, MTA3, GATAD2B, RCOR3, GATAD2A, GSE1, RCOR1, HMG20A, HMG20B, MTA2, MBD2, CDK2AP1, RBBP7, RBBP4, CHD4, ARNT, CDK13, TFAP4, ELAVL1, KDM1A, KDM5B, RAD21, SMARCAD1, ESR1, JUN, ZFPM2, tat, CHD3, MBD3, GRB2,
Protein Size: 515 -
Molekulargewicht
- 59 kDa
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Gen-ID
- 57504
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NCBI Accession
- NM_020744, NP_065795
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Pathways
- Chromatin Binding
Target
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