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PSMC3IP Antikörper (Middle Region)

PSMC3IP Reaktivität: Maus, Human, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Ziege, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2783050
  • Target Alle PSMC3IP Antikörper anzeigen
    PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))
    Bindungsspezifität
    • 15
    • 3
    • 1
    • 1
    Middle Region
    Reaktivität
    • 19
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus, Human, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Ziege, Meerschweinchen
    Wirt
    • 21
    • 1
    Kaninchen
    Klonalität
    • 22
    Polyklonal
    Konjugat
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PSMC3IP Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    RLKNIKAATN HVTPEEKEQV YRERQKYCKE WRKRKRMATE LSDAILEGYP
    Homologie
    Cow: 93%, Dog: 100%, Goat: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PSMC3IP. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human PSMC3IP
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  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 217 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))
    Andere Bezeichnung
    PSMC3IP (PSMC3IP Produkte)
    Synonyme
    PSMC3IP antikoerper, Arabidopsis Hop2 homolog antikoerper, T6J4.9 antikoerper, T6J4_9 antikoerper, C79099 antikoerper, GT198 antikoerper, HOP2 antikoerper, Tbpip antikoerper, HUMGT198A antikoerper, ODG3 antikoerper, TBPIP antikoerper, Gt198 antikoerper, zgc:86785 antikoerper, PSMC3 interacting protein antikoerper, homologous-pairing protein 2 homolog antikoerper, Homologous-pairing protein 2 homolog antikoerper, homologous-pairing protein 2 homolog-like antikoerper, Tat-binding protein 1(Tbp-1)-interacting protein (TBPIP) antikoerper, proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein antikoerper, PSMC3 interacting protein L homeolog antikoerper, PSMC3IP antikoerper, LOC726449 antikoerper, LOC100165513 antikoerper, hop2 antikoerper, psmc3ip antikoerper, LOC100633854 antikoerper, LOC100650062 antikoerper, LOC789362 antikoerper, AHP2 antikoerper, Psmc3ip antikoerper, psmc3ip.L antikoerper
    Hintergrund
    PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.
    Alias Symbols: GT198, HOP2, TBPIP, ODG3, HUMGT198A
    Protein Interaction Partner: PSMC3, PSMC3IP, THRB, ESR2, AR, RXRA, NR3C1,
    Protein Size: 217
    Molekulargewicht
    25 kDa
    Gen-ID
    29893
    NCBI Accession
    NM_016556, NP_057640
    UniProt
    Q9P2W1
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