PSMC3IP Antikörper (Middle Region)

Produktnummer ABIN2783050

Der Kaninchen Polyklonal anti-PSMC3IP Antikörper (ABIN2783050) detektiert spezifisch PSMC3IP in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Maus, Human, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Ziege und Meerschweinchen.

Kurzübersicht für PSMC3IP Antikörper (Middle Region) (ABIN2783050)

Target: PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))

Reaktivität: Maus, Human, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Ziege, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMC3IP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PSMC3IP Antikörper

Bindungsspezifität: Middle Region

Sequenz: RLKNIKAATN HVTPEEKEQV YRERQKYCKE WRKRKRMATE LSDAILEGYP

Homologie: Cow: 93%, Dog: 100%, Goat: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PSMC3IP. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PSMC3IP

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 217 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PSMC3IP

Target: PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))

Andere Bezeichnung: PSMC3IP

Hintergrund: PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.
Alias Symbols: GT198, HOP2, TBPIP, ODG3, HUMGT198A
Protein Interaction Partner: PSMC3, PSMC3IP, THRB, ESR2, AR, RXRA, NR3C1,
Protein Size: 217

Molekulargewicht: 25 kDa

Gen-ID: 29893

NCBI Accession: NM_016556, NP_057640

UniProt: Q9P2W1