VAMP7 Antikörper (C-Term)
Kurzübersicht für VAMP7 Antikörper (C-Term) (ABIN2783037)
Target
Alle VAMP7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- C-Term
-
Verwendungszweck
- Vamp7 Antibody - C-terminal region
-
Sequenz
- DELKGIMVRN IDLVAQRGER LELLIDKTEN LVDSSVTFKT TSRNLARAMC
-
Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against Vamp7. It was validated on Western Blot.
-
Aufreinigung
- Affinity Purified
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Kommentare
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47593-100UG
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.5 mg/mL
-
Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- prevent freeze-thaw cycles
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))
-
Andere Bezeichnung
- Vamp7
-
Hintergrund
-
Background Information: Vamp7 is involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Vamp7 is required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion.Vamp7 is required for calcium regulated lysosomal exocytosis. Vamp7 is involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi.Vamp7 is required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Vamp7 is also required for focal exocytosis of late endocytic vesicles during phagosome formation.
Gene Name: Vesicle-associated membrane protein 7
Alternative Symbols: Syb, VAM, Sybl1, VAMP-7, TI-VAMP
Protein Name: Vesicle-associated membrane protein 7
-
Molekulargewicht
- 25kDa
-
Gen-ID
- 20955
-
NCBI Accession
- NP_035645
-
UniProt
- P70280
Target
-