Cytokeratin 19 Antikörper (N-Term)

Produktnummer ABIN2782974

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Cytokeratin 19 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Kaninchen, Schwein, Rind (Kuh), Pferd und Meerschweinchen.

Kurzübersicht für Cytokeratin 19 Antikörper (N-Term) (ABIN2782974)

Target: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Schwein, Rind (Kuh), Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cytokeratin 19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Cytokeratin 19 Antikörper

Bindungsspezifität: N-Term

Sequenz: TSYSYRQSSA TSSFGGLGGG SVRFGPGVAF RAPSIHGGSG GRGVSVSSAR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against KRT19. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KRT19

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 400 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Cytokeratin 19

Target: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Andere Bezeichnung: KRT19

Hintergrund: KRT19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis.The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CK19, K19, K1CS, MGC15366
Protein Interaction Partner: CEP57L1, PPP1R18, HAUS1, IKZF3, POLR1C, EIF4E2, UBE2I, KRT19, KRT2, KIFC3, FAM124B, CARD9, CCDC146, EIF4ENIF1, C1orf109, AMOTL2, TBC1D7, TFPT, UBC, MDM2, EED, KDM1A, BAG3, PAN2, VCAM1, ITGA4, FN1, EIF4A3, MAGOH, GRB2, CRK, SUMO1, SUMO2, SUMO3, UCHL5, POU5
Protein Size: 400

Molekulargewicht: 44 kDa

Gen-ID: 3880

NCBI Accession: NM_002276, NP_002267

UniProt: P08727