CLN6 Antikörper (C-Term)

Produktnummer ABIN2782927

Der Kaninchen Polyklonal anti-CLN6 Antikörper wird verwendet zum Nachweis von CLN6 in Proben von Human, Maus, Ratte, Hund, Pferd, Meerschweinchen, Rind (Kuh), Kaninchen, Schaf, Zebrafisch (Danio rerio) und Schwein. Er wurde validiert für WB und IHC.

Kurzübersicht für CLN6 Antikörper (C-Term) (ABIN2782927)

Target: CLN6 (Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Meerschweinchen, Rind (Kuh), Kaninchen, Schaf, Zebrafisch (Danio rerio), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLN6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CLN6 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: CLN6 Antibody - C-terminal region

Sequenz: RLFLDSNGLF LFSSFALTLL LVALWVAWLW NDPVLRKKYP GVIYVPEPWA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against CLN6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLN6

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47372-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CLN6

Target: CLN6 (Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6))

Andere Bezeichnung: CLN6

Hintergrund:

Background Information: CLN6 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely CLN6 involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

Gene Name: Ceroid-lipofuscinosis, neuronal 6, late infantile, variant

Alternative Symbols: nclf, CLN4A, HsT18960

Protein Name: Ceroid-lipofuscinosis neuronal protein 6

Molekulargewicht: 36kDa

Gen-ID: 54982

NCBI Accession: NP_060352

UniProt: Q9NWW5

Pathways: Glycosaminoglycan Metabolic Process