LAX1 Antikörper (Middle Region)
Kurzübersicht für LAX1 Antikörper (Middle Region) (ABIN2782914)
Target
Alle LAX1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- LFVLPSTQKL EFTEERDEGC GDAGDCTSLY SPGAEDSDSL SNGEGSSQIS
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Homologie
- Cow: 79%, Human: 100%, Rat: 79%
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Produktmerkmale
- This is a rabbit polyclonal antibody against LAX1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human LAX1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 398 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- LAX1 (Lymphocyte Transmembrane Adaptor 1 (LAX1))
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Andere Bezeichnung
- LAX1
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Hintergrund
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LAX1 is a single-pass type III membrane protein. It negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.
Alias Symbols: FLJ20340, LAX
Protein Interaction Partner: STAMBPL1, GRB7, NDN, UBC, GRAP2, SYK, ZAP70, LCK, GRB2,
Protein Size: 398 -
Molekulargewicht
- 44 kDa
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Gen-ID
- 54900
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NCBI Accession
- NM_017773, NP_060243
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UniProt
- Q8IWV1
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Pathways
- Production of Molecular Mediator of Immune Response
Target
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