HSD17B12 Antikörper (C-Term)

Produktnummer ABIN2782872

Produktdetails anti-HSD17B12 Antikörper

Target: HSD17B12 (Hydroxysteroid (17-Beta) Dehydrogenase 12 (HSD17B12))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SAETFVKSAI KTVGLQTRTT GYVIHSLMGS INSIMPRWMY FKIIMGFSKS

Homologie: Cow: 79%, Dog: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 79%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Hsd17b12. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Hsd17b12

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 312 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HSD17B12

Target: HSD17B12 (Hydroxysteroid (17-Beta) Dehydrogenase 12 (HSD17B12))

Andere Bezeichnung: Hsd17b12 (HSD17B12 Produkte)

Synonyme: KAR antikoerper, SDR12C1 antikoerper, 2610510O05Rik antikoerper, AI172963 antikoerper, KIK-I antikoerper, Kik1 antikoerper, HSD17B12 antikoerper, kar antikoerper, sdr12c1 antikoerper, 17-beta-HSD 12-A antikoerper, fi06g11 antikoerper, wu:fi06g11 antikoerper, zf3.1 antikoerper, zfHSD17B12A antikoerper, zgc:55589 antikoerper, zgc:77599 antikoerper, hydroxysteroid 17-beta dehydrogenase 12 antikoerper, hydroxysteroid (17-beta) dehydrogenase 12 antikoerper, hydroxysteroid (17-beta) dehydrogenase 12 L homeolog antikoerper, hydroxysteroid (17-beta) dehydrogenase 12a antikoerper, HSD17B12 antikoerper, Hsd17b12 antikoerper, hsd17b12.L antikoerper, hsd17b12a antikoerper

Hintergrund: Hsd17b12 catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in females. Hsd17b12 also has 3-ketoacyl-CoA reductase activity, reducing both long chain 3-ketoacyl-CoAs and long chain fatty acyl-CoAs, suggesting a role in long fatty acid elongation.
Alias Symbols: 2610510O05Rik, AI172963, KIK-I, Kik1
Protein Interaction Partner: Eed, DSK2, VPS9, NUB1, UBQLN1, SQSTM1, RAD23B, PSMD4, NBR1,
Protein Size: 312

Molekulargewicht: 35 kDa

Gen-ID: 56348

NCBI Accession: NM_019657, NP_062631

UniProt: O70503

Pathways: Steroid Hormone Biosynthesis