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CHST15 Antikörper (Middle Region)

Der Kaninchen Polyklonal Anti-CHST15-Antikörper wurde für WB validiert. Er ist geeignet, CHST15 in Proben von Human, Ratte, Maus, Hund, Meerschweinchen, Pferd, Rind (Kuh) und Kaninchen zu detektieren.
Produktnummer ABIN2782860

Kurzübersicht für CHST15 Antikörper (Middle Region) (ABIN2782860)

Target

Alle CHST15 Antikörper anzeigen
CHST15 (Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15))

Reaktivität

Human, Ratte, Maus, Hund, Meerschweinchen, Pferd, Rind (Kuh), Kaninchen

Wirt

  • 4
  • 1
Kaninchen

Klonalität

  • 4
  • 1
Polyklonal

Konjugat

  • 5
Dieser CHST15 Antikörper ist unkonjugiert

Applikation

  • 5
  • 2
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 1
    • 1
    • 1
    Middle Region

    Sequenz

    YDNSTDGEPP FLTQDFIHAF QPNARLIVML RDPVERLYSD YLYFASSNKS

    Homologie

    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against GALNAC4S-6ST. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human GALNAC4S-6ST
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 561 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    CHST15 (Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15))

    Andere Bezeichnung

    GALNAC4S-6ST

    Hintergrund

    GALNAC4S-6ST is a sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. GALNAC4S-6ST may also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression, however such results are unclear in vivo.
    Alias Symbols: BRAG, DKFZp781H1369, KIAA0598, MGC34346, RP11-47G11.1, GALNAC4S-6ST
    Protein Interaction Partner: UBC, RRAGD, LYN, HCK,
    Protein Size: 561

    Molekulargewicht

    65 kDa

    Gen-ID

    51363

    NCBI Accession

    NM_015892, NP_056976

    UniProt

    Q7LFX5

    Pathways

    Glycosaminoglycan Metabolic Process
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