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ADCY6 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-ADCY6-Antikörper wurde für WB validiert. Er ist geeignet, ADCY6 in Proben von Human, Maus, Ratte, Rind (Kuh), Schwein, Pferd, Hund und Kaninchen zu detektieren.
Produktnummer ABIN2782842

Kurzübersicht für ADCY6 Antikörper (C-Term) (ABIN2782842)

Target

Alle ADCY6 Antikörper anzeigen
ADCY6 (Adenylate Cyclase 6 (ADCY6))

Reaktivität

Human, Maus, Ratte, Rind (Kuh), Schwein, Pferd, Hund, Kaninchen

Wirt

  • 41
  • 2
  • 1
Kaninchen

Klonalität

  • 41
  • 2
Polyklonal

Konjugat

  • 20
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ADCY6 Antikörper ist unkonjugiert

Applikation

  • 38
  • 17
  • 16
  • 13
  • 13
  • 9
  • 9
  • 7
  • 4
  • 3
  • 3
  • 2
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    LIYLVLLLLG PPATIFDNYD LLLGVHGLAS SNETFDGLDC PAAGRVALKY

    Homologie

    Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against ADCY6. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C terminal region of human ADCY6
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 1115 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    ADCY6 (Adenylate Cyclase 6 (ADCY6))

    Andere Bezeichnung

    ADCY6

    Hintergrund

    ADCY6 is adenylate cyclase 6, which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). The expression of ADCY6 is found in normal thyroid and brain tissues, as well as some tumors, and its expression is significantly higher in one hyperfunctioning thyroid tumor than in normal thyroid tissue.This gene encodes adenylate cyclase 6, which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). The expression of this gene is found in normal thyroid and brain tissues, as well as some tumors, and its expression is significantly higher in one hyperfunctioning thyroid tumor than in normal thyroid tissue. Alternative splicing generates 2 transcript variants.
    Alias Symbols: DKFZp779F075, KIAA0422, AC6
    Protein Interaction Partner: Gnb1, ATXN1, UBC, RAF1, GNAS, CHRNA7,
    Protein Size: 1115

    Molekulargewicht

    125 kDa

    Gen-ID

    112

    NCBI Accession

    NM_020983, NP_066193

    UniProt

    O43306

    Pathways

    EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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