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BMP10 Antikörper (C-Term)

BMP10 Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Pferd, Rind (Kuh), Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2782814
  • Target Alle BMP10 Antikörper anzeigen
    BMP10 (Bone Morphogenetic Protein 10 (BMP10))
    Bindungsspezifität
    • 15
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 55
    • 25
    • 24
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Maus, Ratte, Kaninchen, Hund, Pferd, Rind (Kuh), Meerschweinchen
    Wirt
    • 48
    • 7
    • 1
    • 1
    Kaninchen
    Klonalität
    • 51
    • 6
    Polyklonal
    Konjugat
    • 35
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BMP10 Antikörper ist unkonjugiert
    Applikation
    • 49
    • 17
    • 14
    • 13
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    GYEAYECRGV CNYPLAEHLT PTKHAIIQAL VHLKNSQKAS KACCVPTKLE
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against BMP10. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human BMP10
    Top Product
    Discover our top product BMP10 Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeat freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    BMP10 (Bone Morphogenetic Protein 10 (BMP10))
    Andere Bezeichnung
    BMP10 (BMP10 Produkte)
    Synonyme
    BMP10 antikoerper, si:dkey-13n15.5 antikoerper, Bmp10 antikoerper, BMP9 antikoerper, BMP-10 antikoerper, bone morphogenetic protein 10 antikoerper, BMP10 antikoerper, bmp10 antikoerper, LOC662386 antikoerper, Bmp10 antikoerper
    Hintergrund
    BMP10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. It acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth.
    Alias Symbols: -
    Protein Interaction Partner: BMPR2, ACVR2B, ACVR2A, SERINC3,
    Protein Size: 424
    Molekulargewicht
    46 kDa
    Gen-ID
    27302
    NCBI Accession
    NM_014482, NP_055297
    UniProt
    O95393
    Pathways
    Hormone Activity, Regulation of Muscle Cell Differentiation
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