BMP10 Antikörper (N-Term)

Produktnummer ABIN2782813

Der Kaninchen Polyklonal anti-BMP10 Antikörper wird verwendet zum Nachweis von BMP10 in Proben von Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für BMP10 Antikörper (N-Term) (ABIN2782813)

Target: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMP10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BMP10 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Bmp10 Antibody - N-terminal region

Sequenz: KFATDRTSMP SANIIRSFKN EDLFSQPVSF NGIRKYPLLF NVSIPHHEEV

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Bmp10. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Rat

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47031-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu BMP10

Target: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Andere Bezeichnung: Bmp10

Hintergrund:

Background Information: Bmp10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Bmp10 acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Bmp10 inhibits endothelial cell migration and growth.

Gene Name: Bone morphogenetic protein 10

Alternative Symbols: Bmp10

Protein Name: Bone morphogenetic protein 10

Molekulargewicht: 48kDa

Gen-ID: 500245

NCBI Accession: NP_001026994

UniProt: Q4AEG6

Pathways: Hormone Activity, Regulation of Muscle Cell Differentiation