SEC63 Antikörper (N-Term)
Kurzübersicht für SEC63 Antikörper (N-Term) (ABIN2782761)
Target
Alle SEC63 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- WPRDQNAEQI RLKNIRKVYG RCMWYRLRLL KPQPNIIPTV KKIVLLAGWA
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Homologie
- Cow: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%
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Produktmerkmale
- This is a rabbit polyclonal antibody against SEC63. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SEC63
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 760 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Selective translational repression of truncated proteins from frameshift mutation-derived mRNAs in tumors." in: PLoS biology, Vol. 5, Issue 5, pp. e109, (2007) (PubMed).
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: "Selective translational repression of truncated proteins from frameshift mutation-derived mRNAs in tumors." in: PLoS biology, Vol. 5, Issue 5, pp. e109, (2007) (PubMed).
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- SEC63 (SEC63 Homolog (SEC63))
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Andere Bezeichnung
- SEC63
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Hintergrund
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The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. SEC63 and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may
Alias Symbols: ERdj2, PRO2507, SEC63L, DNAJC23
Protein Interaction Partner: UBC, IRF1, SEC61B, SEC62, GSTK1,
Protein Size: 760 -
Molekulargewicht
- 88 kDa
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Gen-ID
- 11231
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NCBI Accession
- NM_007214, NP_009145
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UniProt
- Q9UGP8
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Pathways
- ER-Nucleus Signaling
Target
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