AFG3L2 Antikörper (Middle Region)
Kurzübersicht für AFG3L2 Antikörper (Middle Region) (ABIN2782736)
Target
Alle AFG3L2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- VNFLKNPKQY QDLGAKIPKG AILTGPPGTG KTLLAKATAG EANVPFITVS
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Homologie
- Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against AFG3L2. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human AFG3L2
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 797 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- AFG3L2 (AFG3-Like Protein 2 (AFG3L2))
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Andere Bezeichnung
- AFG3L2
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Hintergrund
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AFG3L2 is a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. AFG3L2 gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.
Alias Symbols: FLJ25993, SCA28
Protein Interaction Partner: SUMO2, UBC, SUZ12, RNF2, HIPK4, FBXO6, BTK, APP, MAPK8IP2, RAC2, ICT1, BECN1, CLN3, USP50, PHC2,
Protein Size: 797 -
Molekulargewicht
- 88 kDa
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Gen-ID
- 10939
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NCBI Accession
- NM_006796, NP_006787
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UniProt
- Q9Y4W6
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Pathways
- Skeletal Muscle Fiber Development
Target
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